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Healthy Living : November 12, 2019

(NBC15)
Published: Nov. 12, 2019 at 4:13 PM EST
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The wonder of regenerative medicine is before us.

Overview of the current state and future of cell therapy for Age-Related Macular Degeneration will be presented

1. Challenges and Potential of treating Macular Degeneration with cell therapy

2. Strategies

A. Cell Replacement Therapy

B. Cellular Trophic Factors

C. Induced Pluripotential Stem Cells

D. Differentiated Cell Lines

References

1. Ho AC, Chang TS, Samuel M, Williamson P, Willenbucher RF, Malone T. Experience with a subretinal cell-based therapy in patients with geographic atrophy secondary to age-related macular degeneration. Am J Ophthalmol. 2017;179:67-80. doi:10.1016/j.ajo.2017.04.006

2. ^ Schwartz SD, Regillo CD, Lam BL. Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies [Notes:published online October 15, 2014] . Lancet. 2015;385;(9967):509-516. doi:10.1016/S0140-6736(14)61376-3

3. ^ Schwartz SD, Hubschman JP, Heilwell G, et al. Embryonic stem cell trials for macular degeneration: a preliminary report [Notes:published online January 24, 2012] . Lancet. 2012;397(9817):713-720. doi:10.1016/S0140-6736(12)60028-2

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